Iran News ...


05/27/10

Photos: Iran transgenic kids fight heart disease

News Source: Royan Institute, www.royaninstitute.org
Photos by Alieh Saadatpour, Mehr News Agency

Royan scientists have succeeded in producing two transgenic kids, paving the way for Iran to join countries with the technology to generate drugs from transgenic animals. 

In January 2010 following the birth of 'Shangoul' and 'Mangoul', Iran became the first Middle Eastern country to produce transgenic goats with foreign proteins in their milk, which renders them valuable sources of human factor IX for treating individuals suffering from hemophilia B. 

Royan's public relations office announced that two transgenic kids were produced in the center in the past month. Laboratory tests have revealed high concentrations of tissue Plasminogen Activator (tPA) in their blood. 

tPA is the best available medication effective in preventing and treating cardiac arrest and its complications through eliminating the culprit blood clots; however, it is not commonly used due to its high price. A large sum of money is also dedicated for importing small quantities of the drug. 


Dr. Nasr Esfahani

Iranian scientists believe these kids would be capable of producing considerable amounts of tPA by the time they enter the lactation phase. 

One of these kids died within seven days of birth due to gastrointestinal failures; the other kid, however, is reported to be in a good health status.











About: Iran's Royan Institute is a public non-governmental non-profitable organization established in 1991 by the late Dr. saeid Kazemi Ashtiani as an infertility clinic. In 1998 this institute was approved by Ministry of Health as Cell Based Research Center. Now this institute acts as leader of Stem Cell research and also one of the best clinics for infertility treatment. It has 45 scientific members and 53 lab technicians working in 6 departments: stem cells, embryology, genetics, female infertility and andrology.

A Chronological Overview of the Institute Developments

  • The first IVF birth in Tehran (1993)
  • The second ICSI birth in Iran (1995)
  • Iran second success in open testicular biopsy to treat severe male infertility (1996)
  • The first frozen embryo birth in Iran (1996)
  • The first ICSI birth by frozen sperm of a gonadectomized man (1999)
  • The first celebration of the 1000th birth by the assisted conception treatment in Iran (1999)
  • The first human embryonic Stem Cell line establishment (2003)
  • Establishment of Stem Cells research department (2003)
  • The first PGD child born in Iran (2004)
  • The first time use of Adult Stem Cell in treatment of MI during CABG (2004)
  • Production of Insulin Producing Cells from Human Embryonic Stem Cells (2004)
  • Culture of Human Limbal Stem Cells on Chorionic Membrane and use them for corneal injuries
  • (2004)
  • Establishment of the first organized Cord Blood Bank (2005)
  • The first IVM-IVF sheep born in Iran (2006)
  • The first cloned sheep born in Iran (2006)

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