Iranian scientists succeeded to simulate the three-dimensional structure of the proteins efficient in penetration of Human Immunodeficiency Virus (HIV) into body.
Iranian researchers could simulate membrane proteins which play a key role in entrance and connection of HIV to the victim cells. The entrance of the virus will be prevented providing that the protein is inactivated.
Membrane proteins are placed in cell membranes and construction of their three-dimensioned structure with experimental methods is a difficult job so the alternative methods like molecule dynamic simulation is applied so that they can be used for designing medicines efficient in restraining the proteins and treatment of different disease in the future.
Simulation of CCR5 membrane protein has been performed in Iran for the first time. The protein plays a key role in entrance of HIV into the victim cells and the virus will not be able to enter the cell, if the protein activities are restrained. The simulation of the protein will help the researchers find out more about the performances of the proteins.
... Payvand News - 03/11/12 ... --